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Position: Research Fellow in Mathematics and Computational Statistics of Self Organisation in Cell Division
Institution: University of Warwick
Department: Mathematics
Location: Coventry, England, United Kingdom
Duties: To contribute to the research climate within the department and to further its international standing by conducting high-quality relevant research. To work collaboratively with other researchers and senior investigators on the project. To establish a sound research base in order to pursue individual and collaborative research of high quality, consistent with making a substantial research contribution in line with the departmental objectives of maintaining their world-class research performance. To attend and present research findings and papers at lab meetings, academic and professional conferences, and to contribute to the external visibility of the department
Requirements: Possession of a PhD or equivalent in Mathematics/Statistics/Physics/Computer Science or similar, or expect to receive one before the starting date. Excellence in published work in relevant fields. Ability to develop and deliver high quality research and to publish in peer reviewed journals
   
Text: Research Fellow in Mathematics and Computational Statistics of Self Organisation in Cell Division (88190-058) Click here to go back to search results Apply Now Vacancy Type/Job category Research Only Department Mathematics Salary ?29,799-?38,833 per annum Location University of Warwick, Coventry Vacancy Overview Fixed term contract for 4 years. (Start date ideally during summer 2018) Research Fellow in Mathematics and Computational Statistics of Self Organisation in Cell Division. Applications are invited for a postdoctoral research fellow to work on the modelling and statistical inference of chromosome self-organisation during cell division. Cell division is a sophisticated mechanical process whereby chromosomes align to the cell equator, likely involving molecular force sensors and feedback processes. By inferring the mechanics of chromosome movements from 3D experimental trajectories, the aim is to develop a mechanistic dynamic model of the self-organising processes that lead to accurate separation of chromosomes to two daughter cells and how this goes wrong. It thus has relevance to cancer and development disorders. The project will develop and implement Bayesian algorithms to fit (infer) mechanics inspired models to tracked chromosome trajectories generated from high-resolution imaging time-series. The models are stochastic differential equations incorporating multiple ?movement states? (a hidden Markov model, HMM). The project is a collaboration between Burroughs? theory group and an experimental lab in Warwick Medical school. The ideal candidate will have a relevant PhD, e.g. in statistics/mathematics/physics/machine learning, and have a strong background in stochastic modelling and/or computational statistics, e.g. Markov chain Monte Carlo (MCMC), particle filters/sequential Monte Carlo. A background in HMM inference using MCMC algorithms will be beneficial, whilst an ability to programme in MatLab, C++ an advantage. A background in biology is not required. Applications via the HR website should include 1) a letter of application outlining previous research experience/significant results and why you are interested in the post, 2) a CV, 3) a list of publications, and 4) links to a small selection of reprints/preprints/publications from your PhD/latest research post as appropriate. Scientific queries about the project can be made to Prof Burroughs, N.J.Burroughs@warwick.ac.uk, or see his website . Interviews will take place in early June. Job Description Job Purpose To work with Professor Nigel Burroughs on the BBSRC grant ?Kinetochore life-histories: understanding the mechanical events that ensure error-free chromosome segregation?. Duties and Responsibilities To contribute to the research climate within the department and to further its international standing by conducting high-quality relevant research. Research ? To work collaboratively with other researchers and senior investigators on the project. ? To establish a sound research base in order to pursue individual and collaborative research of high quality, consistent with making a substantial research contribution in line with the departmental objectives of maintaining their world-class research performance. ? To attend and present research findings and papers at lab meetings, academic and professional conferences, and to contribute to the external visibility of the department. Administration and Other Activities ? To participate in the teaching, supervision, assessment and examination of students of the University. ? To participate in relevant professional activities, such as departmental research seminars. ? To participate in the organisation of research workshops and other events. The duties and responsibilities outlined are not intended to be an exhaustive list but to provide guidance on the main aspects of the job. The post holder will be required to be flexible in their duties. Person Specification The Person Specification focuses on the knowledge, skills, experience and qualifications required to undertake the role effectively. This is measured by (a) Application Form, (b) Test/Exercise, (c) Interview, (d) Presentation. Essential Criteria 1 Possession of a PhD or equivalent in Mathematics/Statistics/Physics/Computer Science or similar, or expect to receive one before the starting date. (a) Essential Criteria 2 Excellence in published work in relevant fields. (a) (c) Essential Criteria 3 Ability to develop and deliver high quality research and to publish in peer reviewed journals (a) (c) Essential Criteria 4 Ability to work as an independent researcher as well as in a team. (a) (c) Essential Criteria 5 Good effective communication (oral and written) skills, and presentation skills. (a) (c) Desirable Criteria 1 Experience with a programming language and databases (a), (c) Desirable Criteria 2 Willingness to interact with experimentalists (a), (c) Further Particulars If you have not yet been awarded your PhD but are near submission or have recently submitted your PhD, any offers of employment will be made as Research Assistant on Level 5 of the University grade structure (?28,936). Upon award of your PhD and evidence of this fact, you will be promoted to Research Fellow on the first point of the Level 6 of the University grade structure (starts at ?29,799). For further information about the University of Warwick, please read our University Further Particulars . For further information about the department, please visit the departmental website . The Department of Mathematics and the University of Warwick are proud of their diverse community of staff, students, and visitors, and are committed to maintaining an excellent record in teaching and research by ensuring that there is equality of opportunity for all, fostered in an environment of mutual respect and dignity. We are committed to supporting staff to achieve their potential. The Department of Mathematics holds a bronze Athena SWAN award and the University of Warwick holds Athena SWAN silver awards. Athena SWAN is a national initiative that recognizes the advancement of gender equality, representation, progression and success for all in academia. We are supportive of staff with caring responsibilities including a generous maternity/paternity/adoption/parental leave policy, onsite childcare facilities and childcare vouchers scheme. Childcare can be provided for you at the University of Warwick Nursery in order for you to attend the interview. Childcare is subject to availability of places at the Nursery. Recruitment of Ex-Offenders Policy As an organisation using the (DBS) Disclosure and Barring Service to assess applicants? suitability for positions of trust, the University of Warwick complies with the DBS Code of Practice and undertakes not to discriminate unfairly against any subject of a Disclosure on the basis of a conviction or other information revealed. More information is available on the University?s Vacancy pages and applicants may request a copy of the DBS Code of Practice. Other Information The University of Warwick provides an inclusive working and learning environment, recognising and respecting every individual?s differences. We welcome applications from individuals who identify with any of the protected characteristics defined by the Equality Act 2010. Right to work in the UK If you do not yet have the right to work in the UK and/ or are seeking sponsorship under Tier 2 of the UK points-based immigration system please click on this link which contains further information about obtaining right to work in the UK and details about eligibility for sponsorship under Tier 2. Closing Date 4 Jun 2018 Apply Now Email this job to a friend
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