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Position: Research Associate
Institution: University College London
Department: Gt Ormond Street Institute of Child Health
Location: London, United Kingdom
Duties: You will be involved in projects aimed at correcting mutations causing neuromuscular diseases (such as Duchenne muscular dystrophy). The main duties of the post are to design CRISPR/Cas9 to target genes involved in neuromuscular diseases; determine efficacy of nucleases, and the repair of the mutations in cells derived from patients. Techniques will be very varied, and include culture of primary and immortalised cells, molecular cloning, and cell and molecular biology techniques such as immunostaining, nuclease assays, lentiviral or adenoviral production and delivery in vitro and in mouse models, among others
Requirements: Applicants must have a PhD in a relevant subject, will have extensive experience of cell and molecular biology techniques, including cell culture, PCR, RT-PCR, molecular cloning, with CRISPR/Cas9 nucleases and use of viral delivery
   
Text: Research Associate , - Ref:1707189 Click here to go back to search results Apply Now UCL Department / Division Gt Ormond Street Institute of Child Health Location of position London Grade 7 Hours Full Time Salary (inclusive of London allowance) ?34,635 - ?41,864 per annum Duties and Responsibilities Applications are invited for a Research Associate to join a well-funded, highly interactive research group led by Professor Francesco Muntoni which is investigating the molecular basis of, and treatment for, neuromuscular diseases. You will be involved in projects aimed at correcting mutations causing neuromuscular diseases (such as Duchenne muscular dystrophy). The main duties of the post are to design CRISPR/Cas9 to target genes involved in neuromuscular diseases; determine efficacy of nucleases, and the repair of the mutations in cells derived from patients. Techniques will be very varied, and include culture of primary and immortalised cells, molecular cloning, and cell and molecular biology techniques such as immunostaining, nuclease assays, lentiviral or adenoviral production and delivery in vitro and in mouse models, among others. This post offers an exciting opportunity for candidates seeking to carry out research in neuromuscular diseases within an established national centre of excellence. This post funded for 11 months in the first instance. Key Requirements Applicants must have a PhD in a relevant subject, will have extensive experience of cell and molecular biology techniques, including cell culture, PCR, RT-PCR, molecular cloning, with CRISPR/Cas9 nucleases and use of viral delivery. Further Details A job description and person specification can be accessed at the bottom of the page. To apply for the vacancy please click on the ?Apply Now? button below. If you have any queries regarding the vacancy or the application process, please contact Madhur Sharma on ich.hr@ucl.ac.uk UCL Taking Action for Equality Closing Date 31 Jan 2018 Latest time for the submission of applications 23:59 Interview date 14 February 2018 Our department holds an Athena SWAN Silver award, in recognition of our commitment and success in addressing gender equality. This appointment is subject to UCL Terms and Conditions of Service for Research and Support Staff. Please use these links to find out more about the UCL Terms and Conditions related to this job, employee benefits that we offer and further information about UCL . Job Description & Person Specification Apply Now
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