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Position: Research Fellow
Institution: University College London
Department: UCL Institute of Child Health
Location: London, United Kingdom
Duties: The post holder will join a department pioneering first-in-man CAR T cell therapies for childhood cancers. Our group is interested in probing the biological characteristics which underpin efficacy of CAR T cell therapy. In the first instance, the research will involve analysis of patient samples using state of the art multi-modal molecular biology techniques including single cell transcriptomics, genomics, epigenetic profiling as well as cross-correlation with multiparametric phenotyping and functional CAR T cell assays both in vitro and in vivo
Requirements: Applicants must have a PhD in a relevant subject, will have experience in generating/analysing next generation transcriptome/genome sequencing data, cell and molecular biology techniques, including cell culture, PCR, molecular cloning. Candidates should also have experience of functional T cell assays and in vivo tumour models
   
Text: Research Fellow, - Ref:1791376 Click here to go back to search results Apply Now UCL Department / Division UCL Institute of Child Health Specific unit / Sub department Developmental Biology and Cancer Programme Location of position London Grade 7 Hours Full Time Salary (inclusive of London allowance) ?35,328 ? ?38,303 per annum Duties and Responsibilities The post holder will join a department pioneering first-in-man CAR T cell therapies for childhood cancers. Our group is interested in probing the biological characteristics which underpin efficacy of CAR T cell therapy. Funding has been made available through a CRUK accelerator award and is available for 3 years with a possibility of extension of the post until November 2023. In the first instance, the research will involve analysis of patient samples using state of the art multi-modal molecular biology techniques including single cell transcriptomics, genomics, epigenetic profiling as well as cross-correlation with multiparametric phenotyping and functional CAR T cell assays both in vitro and in vivo. This post offers an exciting opportunity for candidates seeking to carry out research in gene-engineered cellular therapies within an internationally-recognised centre of excellence. Key Requirements Applicants must have a PhD in a relevant subject, will have experience in generating/analysing next generation transcriptome/ genome sequencing data, cell and molecular biology techniques, including cell culture, PCR, molecular cloning. Candidates should also have experience of functional T cell assays and in vivo tumour models. Further Details A job description and person specification can be accessed at the bottom of this page. To apply for the vacancy please click on the ?Apply Now? button below. If you have any queries regarding the vacancy or the application process, please contact ICH HR at ich.hr@ucl.ac.uk . UCL Taking Action for Equality Closing Date 12 Mar 2019 Latest time for the submission of applications 23.59 Interview date TBC Our department holds an Athena SWAN Silver award, in recognition of our commitment and demonstrable impact in advancing gender equality. This appointment is subject to UCL Terms and Conditions of Service for Research and Support Staff. Please use these links to find out more about UCL working life including the benefits we offer and UCL Terms and Conditions related to this job. Job Description & Person Spec Apply Now
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