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Position: Doctoral Candidate/PhD student - Cancer Metabolism and Microbiome Research
Institution: University of Luxembourg
Location: Luxembourg City, Luxembourg
Duties: The project entitled ‘Untargeted Approaches to Identify Metabolites Involved in Colon Cancer Development and Progression’ involves the development of untargeted metabolomics analysis pipelines to identify metabolites whose levels differ significantly e.g. between control and tumour samples from colorectal cancer patients or between healthy control and patient plasma samples. Elucidation of the organismal origin of these metabolites (microbiome- or human-derived) will be assisted by metabolic modelling
Requirements: Master degree in Chemistry, Biochemistry, Molecular Biology, Biotechnology or a related discipline. Strong background in metabolic biochemistry and analytical chemistry, as well as solid notions in bio-/cheminformatics and biostatistics. Previous hands-on experience with chromatography and mass spectrometry techniques
   
Text: UOL02613 01-Mar-2019 Company Text The University of Luxembourg is a multilingual, international research University. Luxembourg is a dynamic, multicultural country in the heart of Europe with a strong research and development base supported by important organisational resources. The Luxembourg Centre for Systems Biomedicine (LCSB) at the University of Luxembourg offers state-of-the-art facilities and an excellent training environment for early-stage researchers, in particular in the biomedical sciences. The Enzymology & Metabolism and Environmental Cheminformatics Research Groups at the LCSB are looking to hire a PhD student as part of the MICROH DTU, an interdisciplinary doctoral training unit which aims to study interactions within and between microbiomes in relation to two major healthcare challenges of our time, i.e. the spread of antimicrobial resistance genes and the increasing prevalence of chronic diseases. Ref : RCREQ0001411 - (R-AGR-3400-12-C) MICROH DT Initial 14 months fixed-term contract, renewable depending on thesis progress evaluation. Full-time position (40h/week) Student and employee status (36 months study program, as per university standards, with project funding available for up to 48 months) Earliest starting date March 1st, 2019 (position will be advertised until filled) Your Role The project entitled ‘Untargeted Approaches to Identify Metabolites Involved in Colon Cancer Development and Progression’ involves the development of untargeted metabolomics analysis pipelines to identify metabolites whose levels differ significantly e.g. between control and tumour samples from colorectal cancer patients or between healthy control and patient plasma samples. Elucidation of the organismal origin of these metabolites (microbiome- or human-derived) will be assisted by metabolic modelling. For further information, please contact: Dr. Carole Linster (carole.linster@uni.lu) Your Profile Master degree in Chemistry, Biochemistry, Molecular Biology, Biotechnology or a related discipline Strong background in metabolic biochemistry and analytical chemistry, as well as solid notions in bio- /cheminformatics and biostatistics Previous hands-on experience with chromatography and mass spectrometry techniques Experience with metabolic modelling will be considered an advantage Excellent English writing and speaking skills will be essential We offer 36 months study program, as per university standards, with project funding available for up to 48 month Competitive remuneration; contract subject to public national security system benefits A dynamic, exciting and equal opportunity international research environment Further Information Applications (in English) should quote Ref RCREQ0001411 and include: Cover letter indicating your motivation for this position, relevant past experience and future interests Detailed curriculum vitae, including publications Copy of the relevant diplomas Contact details of three referees Please apply ONLINE until March 1st, 2019 (or until filled).
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