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Position: Research Fellow in Synapse Degeneration and Pathology in Alzheimer's disease
Institution: University College London
Department: Division of Biosciences
Location: London, United Kingdom
Duties: Applications are invited for a postdoctoral research fellow to study the cellular and molecular mechanisms that regulate synapse degeneration in the mammalian nervous system. The work will involve analyses of synaptic changes in vivo, in brain slices and cultured neurons using state-of-the-art imaging techniques combined with the latest molecular genetic methods and electrophysiology to determine changes in network connectivity. Some of the main duties and responsibilities of the post are to develop, plan and undertake scientific research under supervision within a specific research project and work as a member of a research team and to design, develop, refine and analyse experiments in order to obtain reliable and publishable data
Requirements: The successful candidate must have a PhD (or be studying towards it) in relevant subject area. Successful candidate must have a strong interest in understanding the mechanisms that modulate synaptic plasticity and synapse degeneration. Experience in cellular neuroscience, cell imaging techniques and/or electrophysiology are also essential
   
Text: Research Fellow in Synapse Degeneration and Pathology in Alzheimer's disease, - Ref:1776049 Click here to go back to search results Apply Now UCL Department / Division Division of Biosciences Specific unit / Sub department Research Department of Cell and Developmental Biology Location of position London Grade 7 Hours Full Time Salary (inclusive of London allowance) ?35,328 - ?42,701 per annum Duties and Responsibilities Applications are invited for a postdoctoral research fellow to study the cellular and molecular mechanisms that regulate synapse degeneration in the mammalian nervous system. Our lab has made significant contributions to our current understanding of the function of Wnt signalling in synapse formation, plasticity and synapse maintenance. The successful applicant will determine how deficiency in Wnt signalling triggers synapse loss and synaptic dysfunction in the adult brain. The project will be under the direction of Professor Patricia Salinas at UCL. The work will involve analyses of synaptic changes in vivo, in brain slices and cultured neurons using state-of-the-art imaging techniques combined with the latest molecular genetic methods and electrophysiology to determine changes in network connectivity. Some of the main duties and responsibilities of the post are to develop, plan and undertake scientific research under supervision within a specific research project and work as a member of a research team and to design, develop, refine and analyse experiments in order to obtain reliable and publishable data. The post is funded by the Alzheimer?s Society and it is funded until 28th February 2021. Further Details Further particulars, including a job description and person specification, can be accessed at the bottom of this page. Please ensure you read these carefully before applying for the post. Informal enquiries should be addressed to Professor Patricia Salinas (email: p.salinas@ucl.ac.uk, telephone: 020 7679 4225). For an outline of the lab?s research interests https://www.ucl.ac.uk/biosciences/departments/cdb/people/patricia-salinas/salinas-lab To apply for the vacancy please click on the ?Apply Now? button below. If you have any queries regarding the application process please contact Biosciences staffing on biosciences.staffing@ucl.ac.uk quoting the vacancy reference number: 1776049. UCL Taking Action for Equality We will consider applications to work on a part-time, flexible and job share basis wherever possible. Closing Date 10 Feb 2019 Latest time for the submission of applications 23:59 Interview date TBC Our department holds an Athena SWAN Bronze award, in recognition of our commitment to advancing gender equality. This appointment is subject to UCL Terms and Conditions of Service for Research and Support Staff. Please use these links to find out more about UCL working life including the benefits we offer and UCL Terms and Conditions related to this job. Job Description and Person Specification Apply Now
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