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Position: Associate - Developmental Biology
Institution: University of Sheffield
Department: Biomedical Science
Location: Sheffield, South Yorkshire, United Kingdom
Duties: You will carry out experiments to understand how the planar polarity proteins Fat and Dashsous regulate anisotropic growth by converting tissue-level patterning cues into cell-level polarity information, and work alongside a computational modeller who will use the data to make experimentally testable predictions. We will focus on the Drosophila larval wing disc, where competing hypotheses have been proposed for the mechanisms underlying coordination of growth and planar polarisation. Experimental methods will be spatiotemporal manipulation of gene expression combined with fixed and live microscopy of tissue to obtain quantitative data on cell behaviours
Requirements: You will have a PhD (or equivalent experience) and practical experience in cell or developmental biology as relevant to animal development, be able to demonstrate good quantitative skills, and have a proven record of research productivity
   
Text: Find a Job Find PhDs Careers Advice Jobs by Email Recruiters Your Account Find a Job Find PhDs Careers Advice Jobs by Email Your Account Recruiters Back to search results Associate in Developmental Biology University of Sheffield - Faculty of Science - Department of Biomedical Science Location: Sheffield Salary: £31,302 to £33,199 per annum, Grade 7 Hours: Full Time Contract Type: Fixed-Term/Contract Placed On: 2nd November 2018 Closes: 4th December 2018 Job Ref: UOS020789 Contract Type: Fixed term for 30 months A BBSRC-funded Research Associate position is available for a candidate with a background relevant to experimental dissection of dynamic biological processes to join an interdisciplinary team investigating the coordination of tissue patterning and growth using Drosophila epithelial development as a model system. This is an excellent opportunity for a biologist to work in a leading developmental biology lab in a project combining experimental and computational modelling approaches. The Strutt lab (Department of Biomedical Science, University of Sheffield) is a world leader in studying the planar polarity signalling pathways that control coordinated cell polarisation in animal tissues. In this collaborative project with Dr Alexander Fletcher (School of Mathematics and Statistics, University of Sheffield) we are now combining our biological expertise with mathematical modelling approaches, to build an integrated understanding of how tissue patterning and growth are coordinated to achieve consistent organ shape and size during animal development. You will carry out experiments to understand how the planar polarity proteins Fat and Dashsous regulate anisotropic growth by converting tissue-level patterning cues into cell-level polarity information, and work alongside a computational modeller who will use the data to make experimentally testable predictions. We will focus on the Drosophila larval wing disc, where competing hypotheses have been proposed for the mechanisms underlying coordination of growth and planar polarisation. Experimental methods will be spatiotemporal manipulation of gene expression combined with fixed and live microscopy of tissue to obtain quantitative data on cell behaviours. The overall aim will be to investigate the relative contributions of specific cell behaviours to overall tissue behaviour, using modelling to help disentangle growth and patterning. You will have a PhD (or equivalent experience) and practical experience in cell or developmental biology as relevant to animal development, be able to demonstrate good quantitative skills, and have a proven record of research productivity. You will be expected to have excellent interpersonal and communication skills, and be able to work independently to a high standard while meeting deadlines. We’re one of the best not-for-profit organisations to work for in the UK. The University’s Total Reward Package includes a competitive salary, a generous Pension Scheme and annual leave entitlement, as well as access to a range of learning and development courses to support your personal and professional development. We build teams of people from different heritages and lifestyles from across the world, whose talent and contributions complement each other to greatest effect. We believe diversity in all its forms delivers greater impact through research, teaching and student experience. We value your feedback on the quality of our adverts. If you have a comment to make about the overall quality of this advert, or its categorisation then please Advert information Type / Role: Subject Area(s): Location(s): Job tools More jobs from University of Sheffield More jobs like this Join in and follow us Copyright © jobs.ac.uk 1998 - 2018 Copyright © jobs.ac.uk 1998 - 2018 IE11 Trigger Browser Upgrade Recommended jobs.ac.uk has been optimised for the latest browsers. For the best user experience, we recommend viewing jobs.ac.uk on one of the following:
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