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Position: Research Fellow
Institution: University College London
Department: MRC Laboratory for Molecullar Cell Biology
Location: London, United Kingdom
Duties: A postdoctoral Research Fellow position is available in Professor de Bruin’s research group at the MRC Laboratory for Molecular Biology, University College London. The long-term goal of the de Bruin lab is to attain a thorough understanding of the role of cell cycle transcription in the maintenance of genome integrity. The aim of this project is to establish the role of E2F activity in oncogene-induced replication stress using quantitative cell biology and single-cell approaches. The overall aim of this work is to exploit deregulated E2F activity to selectively kill cancer cells
Requirements: We are seeking an enthusiastic and motivated scientist who has completed or is about to complete a PhD in quantitative cell biology and is capable of working to a high standard. Expertise in both experimental and computational work is a requirement and experience in single-cell time-lapse approaches would be a distinct advantage. Experience in working with mammalian cell cultures and CRISPR Cas9 would be a clear advantage and knowledge of transcriptional regulatory mechanisms desirable. An excellent track record, indicating competitiveness for postdoctoral fellowships, is highly desirable. Good communication and organisational skills are essential
   
Text: Research Fellow, - Ref:1758743 Click here to go back to search results Apply Now UCL Department / Division MRC Laboratory for Molecullar Cell Biology Location of position London Grade 7 Hours Full Time Salary (inclusive of London allowance) ?35,328 to ?42,701 per annum Duties and Responsibilities A postdoctoral Research Fellow position is available in Professor de Bruin?s research group at the MRC Laboratory for Molecular Biology, University College London. The long-term goal of the de Bruin lab is to attain a thorough understanding of the role of cell cycle transcription in the maintenance of genome integrity. The aim of this project is to establish the role of E2F activity in oncogene-induced replication stress using quantitative cell biology and single-cell approaches. The overall aim of this work is to exploit deregulated E2F activity to selectively kill cancer cells. The position is available for two years in the first instance and is funded by Cancer Research UK. Salary is at Grade 7 from ?35,358 to ?42,701 per annum inclusive of London Weighting. If the PhD has not yet been awarded, the appointment will be made at Research Assistant Grade 6B at ?30,922 to ?32,607 per annum inclusive, with payment at Grade 7 being backdated to the date of final submission of the PhD thesis. Details of our research may be found online at http://www.ucl.ac.uk/lmcb/users/rob-de-bruin . Key Requirements We are seeking an enthusiastic and motivated scientist who has completed or is about to complete a PhD in quantitative cell biology and is capable of working to a high standard. Expertise in both experimental and computational work is a requirement and experience in single-cell time-lapse approaches would be a distinct advantage. Experience in working with mammalian cell cultures and CRISPR Cas9 would be a clear advantage and knowledge of transcriptional regulatory mechanisms desirable. An excellent track record, indicating competitiveness for postdoctoral fellowships, is highly desirable. Good communication and organisational skills are essential. Further Details We are located on the UCL campus at Gower Street in central London. The UCL campus presents a vibrant and diverse research environment in the heart of the most exciting city in Europe. Informal inquiries may be addressed to r.debruin@ucl.ac.uk For assistance with the application process, please contact Lucy Newman ( lucy.newman@ucl.ac.uk ). Please apply via the link below and see link for Job Description/Person Specification UCL Taking Action for Equality Closing Date 20 Nov 2018 Latest time for the submission of applications 23:59 Interview date TBC Our department holds an Athena SWAN Gold award, in recognition of our long-term commitment and 'beacon' status in advancing gender equality. This appointment is subject to UCL Terms and Conditions of Service for Research and Support Staff. Please use these links to find out more about UCL working life including the benefits we offer and UCL Terms and Conditions related to this job. Job Description and Person Specification - 1758743 Research Fellow Apply Now
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