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Position: Research Associate (Chemist/Chemical Biologist) - DNA Base Modifications and Their Epigenetic Functions
Institution: University of Cambridge
Department: Chemistry
Location: Cambridge, Cambridgeshire, United Kingdom
Duties: We seek postdoctoral scientists to investigate the epigenetic role of chemically modified nucleic acid bases. This is an interdisciplinary project that encompasses organic and biophysical chemistry, chemical and molecular biology and genomics. We look to appoint chemists or chemical biologists to carry out research on how chemically modified bases affect the structure and function of DNA. Part of the investigations will involve a consideration of the chemistry and enzymology of nucleic acids, protein-DNA interactions, chromatin structure and transcription. This will enable us to gain a deeper understanding of epigenetic regulation in normal and disease states using human, mouse and parasite models
Requirements: Candidates should have (or be about to receive) a PhD in a relevant discipline
   
Text: Research Associate - Chemists/Chemical biologists to study DNA base modifications and their epigenetic functions (Fixed Term) Fixed-term: The funds for this post are available for 2 years in the first instance. We seek postdoctoral scientists to work with Professor Sir Shankar Balasubramanian on a Wellcome Trust-funded programme to investigate the epigenetic role of chemically modified nucleic acid bases. This is an interdisciplinary project that encompasses organic and biophysical chemistry, chemical and molecular biology and genomics. See https://www.balasubramanian.co.uk for further information. We look to appoint chemists or chemical biologists to carry out research on how chemically modified bases affect the structure and function of DNA. Part of the investigations will involve a consideration of the chemistry and enzymology of nucleic acids, protein-DNA interactions, chromatin structure and transcription. This will enable us to gain a deeper understanding of epigenetic regulation in normal and disease states using human, mouse and parasite models. The successful candidate will have a capacity for innovation and creativity. Strong communication skills and the ability to work effectively as part of a multi-disciplinary team will be important. Experience in nucleic acid chemistry and working in an interdisciplinary environment with molecular/cell biologists or biochemists would be an advantage. Candidates should have (or be about to receive) a PhD in a relevant discipline. The positions are available from November 2018 onwards. Previous applicants need not apply. To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form. Please ensure that you upload a 2-page Curriculum Vitae (CV), a covering letter and publications list in the Upload section of the online application. If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application. For queries this post, please contact Jo Lockhart, PA to Professor Sir Shankar Balasubramanian, email: BalasubramanianRecruitment@ch.cam.ac.uk Please quote reference MA16981 on your application and in any correspondence about this vacancy. The Department holds an Athena SWAN silver award for women in Science, Technology, Engineering, Mathematics, and Medicine. The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK. Further information Further information Apply online Department/Location Department of Chemistry Salary £32,236-£39,609 Reference MA16981 Category Research Published 5 October 2018 Closing date 5 November 2018
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